Alarmins in chronic noncommunicable diseases: Atherosclerosis, diabetes and cancer

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• 作者：Raluca M Boteanu^a ; Viorel I Suica^a ; Elena Uyy^a ; Luminita Ivan^a ; Simona O Dima^b ; Irinel Popescu^b ; Maya Simionescu^a ; Felicia Antohe^a ; ^{felicia.antohe@icbp.ro}
• 关键词：Alarmins ; Proteomics ; Atherosclerosis ; Diabetes ; Cancer
• 刊名：Journal of Proteomics
• 出版年：2017
• 出版时间：5 February 2017
• 年：2017
• 卷：153
• 期：Complete
• 页码：21-29
• 全文大小：895 K
• 卷排序：153

文摘

Alarmins are potential biomarkers of chronic noncommunicable diseases. High lipid stress induces increased expression of HSPs in endothelial cells. HMGB1 is highly associated with inflammation in atherosclerosis and diabetes. Mass spectrometry indicated a specific pattern of S100 proteins in the pancreatic cancer.