1,25-Dihydroxyvitamin D₃ targeting VEGF pathway alleviates house dust mite (HDM)-induced airway epithelial barrier dysfunction

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• 作者：Ruhui Zhang^a ; ¹ ; Hangming Dong^a ; ¹ ; Haijin Zhao^a ; ¹ ; Liqin Zhou^a ; ¹ ; Fei Zou^b ; Shaoxi Cai^a ; ^{caishaox@fimmu.com}
• 关键词：Asthma ; Airway epithelial barrier ; HDM ; 1 ; 25(OH)2D3 ; VEGF ; PI3K/AKT pathway phosphorylation
• 刊名：Cellular Immunology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：312
• 期：Complete
• 页码：15-24
• 全文大小：3281 K
• 卷排序：312

文摘

1,25(OH)2D3 alleviated HDM-induced airway epithelial barrier dysfunction. 1,25(OH)2D3 inhibited HDM-induced VEGF expression by PI3K/Akt pathway. 1,25(OH)2D3 inhibited VEGF-induced airway barrier disruption.