Involvement of mast cells and histamine in edema induced in mice by Scolopendra viridicornis centipede venom

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Involvement of mast cells and histamine in edema induced in mice by Scolopendra viridicornis centipede venom

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作者：Bianca C.L.F. Tá ; vora^a ; Louise F. Kimura^a ; Marta M. Antoniazzi^b ; Thiago M. Chiariello^c ; Eliana L. Faquim-Mauro^a ; Katia C. Barbaro^a ; ^{katia.barbaro@butantan.gov.br" class="auth_mail" title="E-mail the corresponding author}
关键词：Centipede venom ; Scolopendra ; Inflammation ; Mast cell and histamine
刊名：Toxicon
出版年：2016
出版时间：October 2016
年：2016
卷：121
期：Complete
页码：51-60
全文大小：2290 K

文摘

•: Mast cells and histamine are involved in the inflammatory cascade developed by Scolopendra viridicornis venom.
•: The role of histamine in edema formation induced by Scolopendra viridicornis venom is mainly via the H₁ receptor.
•: Scolopendra viridicornis venom has a direct effect on mast cells lines in vitro.
•: Scolopendra viridicornis venom promotes cytokines, chemokine and eicosanoid production by mast cell lines in vitro.

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