Prenatal exposure to OPs was previously found to be adversely related to child IQ.

We show that certain life stressors are negatively associated with children⿿s IQ.

Prenatal OP exposure has stronger association with IQ in youth with more life stress.

The types of stressors that interact with prenatal OP exposure vary by child sex.

This is the first human study of interaction of pesticides and social stressors.