Patient-reported outcomes (PROs) are among the most relevant outcome measures.

It is unknown which out of the numerous PROs are most important in pancreatic cancer.

This two-round Delphi survey included 150 patients and 78 health care professionals (HCPs).

A total of 17 PROs were selected by both patients and HCPs.

This core set of PROs may be incorporated in pancreatic cancer care and research.