Comorbid conditions associated with Parkinson's disease: A longitudinal and comparative study with Alzheimer disease and control subjects

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• 作者：D. Santos Garcí ; a^a ; ^{diegosangar@yahoo.es} ; E. Suá ; rez Castro^a ; I. Expó ; sito^a ; T. de Deus^a ; C. Tuñ ; as^a ; A. Aneiros^a ; M. Ló ; pez Ferná ; ndez^a ; D. Nú ; ñ ; ez Arias^b ; M. Bermú ; dez Torres^c
• 关键词：AD ; Alzheimer disease ; ADLS ; Schwab & England Activities of Daily Living Scale ; BDI ; Beck Depression Inventory ; CI ; Charlson Index ; CPS ; Comorbidity-Polypharmacy Score ; ECM ; Elixhauser Comorbidity Measure ; H&Y ; Hoehn & Yahr ; ICD-10 ; International Classification of Diseases ; Tenth Revision ; NMSS ; Non-Motor Symptoms Scale ; PD ; Parkinson's disease ; UPDRS ; Unified Parkinson's Disease Rating Scale
• 刊名：Journal of the Neurological Sciences
• 出版年：2017
• 出版时间：15 February 2017
• 年：2017
• 卷：373
• 期：Complete
• 页码：210-215
• 全文大小：313 K
• 卷排序：373

文摘

Comorbidity is frequent in Parkinson´s disease (PD) patients and increases significantly over time. Comorbidity predicts mortality in PD patients over time independently of the effects of other factors. Comorbidity seems to be higher in PD patients than in controls but equivalent to Alzheimer´s disease (AD) patients. Polypharmacy is more frequent in PD and AD patients than in controls. Total number of non-antiparkinsonian drugs could be used as a surrogate marker of comorbidity in PD patients.