Dysrhythmia of timed movements in Parkinson壮s disease and freezing of gait

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Dysrhythmia of timed movements in Parkinson壮s disease and freezing of gait

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作者：Christopher M. Tolleson^a ; ¹ ; David G. Dobolyi^b ; ¹ ; Olivia C. Roman^a ; Kristen Kanoff^a ; Scott Barton^c ; Scott A. Wylie^a ; Michael Kubovy^b ; Daniel O. Claassen^a ; ^{daniel.claassen@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author}
关键词：AIC ; Akaike information criterion ; CES-D ; Center for Epidemiological Studies Depression Scale ; FOG ; Freezing of gait ; FOG-Q ; Freezing of Gait Questionnaire ; ISI ; Inter-stimulus interval ; ITI ; Inter-Tap Intervals ; LMM ; Linear Mixed Models ; MAD ; Median absolute deviance ; ms ; Millisecond ; MoCA ; Montreal Cognitive Assessment ; OHC ; Older healthy controls ; PIGD ; Postural instability gait disorder ; PD-C ; Parkinson壮s disease Controls ; PD-FOG ; Parkinson壮s disease patients with FOG ; PDQ-39 ; Parkinson壮s Di
刊名：Brain Research
出版年：2015
出版时间：22 October 2015
年：2015
卷：1624
期：Complete
页码：222-231
全文大小：1223 K

文摘

•: Parkinson壮s patients are able to accurately tap in synchrony with an auditory cue.
•: In the absence of a cue, all patients tap ahead of the beat (motor hastening).
•: Motor hastening worsens in patients with gait freezing, tracking clinical severity.
•: Following a short cessation of movement, only freezers hasten more.

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