Vitamin D, PTH and the risk of overall and disease-specific mortality: Results of the Longitudinal Aging Study Amsterdam

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Vitamin D, PTH and the risk of overall and disease-specific mortality: Results of the Longitudinal Aging Study Amsterdam

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作者：Jamila El Hilali^a ; ¹ ; ^{j.elhilali@hotmail.nl" class="auth_mail" title="E-mail the corresponding author} ; ^{j.elhilali@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Elisa J. de Koning^a ; ^b ; ¹ ; ^{ej.dekoning@vumc.nl" class="auth_mail" title="E-mail the corresponding author} ; Adriana J. van Ballegooijen^b ; ^c ; ^{a.j.van.ballegooijen@vu.nl" class="auth_mail" title="E-mail the corresponding author} ; Paul Lips^b ; ^d ; ^{p.lips@vumc.nl" class="auth_mail" title="E-mail the corresponding author} ; Evelien Sohl^a ; ^b ; ^{e.sohl@vumc.nl" class="auth_mail" title="E-mail the corresponding author} ; Harm W.J. van Marwijk^b ; ^e ; ^f ; ^{harm.vanmarwijk@manchester.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Marjolein Visser^b ; ^c ; ^d ; ^{m.visser@vu.nl" class="auth_mail" title="E-mail the corresponding author} ; Natasja M. van Schoor^a ; ^b ; ^{nm.vanschoor@vumc.nl" class="auth_mail" title="E-mail the corresponding author}
关键词：Vitamin D ; PTH ; All-cause mortality ; Cardiovascular mortality ; Cancer mortality ; Older adults
刊名：Journal of Steroid Biochemistry and Molecular Biology
出版年：2016
出版时间：November 2016
年：2016
卷：164
期：Complete
页码：386-394
全文大小：523 K

文摘

•: Low 25(OH)D levels were associated with a higher risk of overall mortality.
•: Men with high PTH levels had a higher risk of overall and cardiovascular mortality.
•: No associations of 25(OH)D or PTH with cancer mortality were observed.
•: The association of 25(OH)D with overall mortality was (partly) mediated by PTH.
•: Serum 25(OH)D and PTH should be regarded as important health markers.

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