Conventional and microwave-assisted synthesis, characterization, DFT calculations, in vitro DNA binding and cleavage studies of potential chemotherapeutic diorganotin(IV) mandelates

设为首页

收藏本站

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Readers' Guide

Opening Hours
Collections
Help Via Email

Publications

Electronic Information Resources

Conventional and microwave-assisted synthesis, characterization, DFT calculations, in vitro DNA binding and cleavage studies of potential chemotherapeutic diorganotin(IV) mandelates

详细信息查看全文

作者：Mridula ; Mala Nath ; ^{malanfcy@iitr.ernet.in" class="auth_mail" title="E-mail the corresponding author} ; ^{malanfcy@gmail.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Diorganotin(IV) mandelates ; Microwave-assisted synthesis ; DFT ; Thermogravimetric analyses ; In vitro CT-DNA binding studies ; pBR322 plasmid cleavage
刊名：Journal of Photochemistry and Photobiology B: Biology
出版年：2016
出版时间：September 2016
年：2016
卷：162
期：Complete
页码：348-360
全文大小：1872 K

文摘

•: Microwave assisted green synthesis of diorganotin(IV) mandelates.
•: Their geometries have been optimized by DFT calculations.
•: UV–Vis and fluorescence titrations suggest an intercalative mode of binding with CT-DNA.
•: They exhibited effective cleavage of supercoiled plasmid pBR322 DNA.