CT imaging of bone and bone marrow infiltration in malignant melanoma—Challenges and limitations for clinical staging in comparison to 18FDG-PET/CT

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CT imaging of bone and bone marrow infiltration in malignant melanoma—Challenges and limitations for clinical staging in comparison to 18FDG-PET/CT

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作者：Georg Bier^a ; ^{georg.bier@med.uni-tuebingen.de" class="auth_mail" title="E-mail the corresponding author} ; Vera Hoffmann^a ; Christopher Kloth^a ; Ahmed E. Othman^a ; Thomas Eigentler^b ; Claus Garbe^b ; Christian La Fougè ; re^c ; Christina Pfannenberg^a ; Konstantin Nikolaou^a ; Bernhard Klumpp^a
关键词：18F-FDG-PET/CT ; 18F-fluododeoxyglucose positron emission tomography/computed tomography ; AJCC ; American Joint Committee on Cancer ; BM ; bone marrow ; BMA ; bone marrow attenuation ; CECT ; contrast-enhanced computed tomography ; CT ; computed tomography ; HU ; hounsfield unit ; LSO ; lutetium oxyorthosilicate ; MRP ; multiplanar reformations ; MRI ; magnetic resonance imaging ; NPV ; negative predictive value ; PPV ; positive predictive value ; ROI ; region of interest ; SD ; standard deviation
刊名：European Journal of Radiology
出版年：2016
出版时间：April 2016
年：2016
卷：85
期：4
页码：732-738
全文大小：964 K

文摘

•: Disseminated bone marrow involvement is accompanied by high mortality.
•: The diagnostic value of CT for detection of bone marrow involvement is limited.
•: PET/CT is recommendable for melanoma patients with obscure elevation of serological markers.

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