Sphingosine induces the aggregation of imine-containing peroxidized vesicles

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

Sphingosine induces the aggregation of imine-containing peroxidized vesicles

详细信息查看全文

作者：Noemi Jimé ; nez-Rojo^a ; Ana R. Viguera^a ; M. Isabel Collado^b ; Kacee H. Sims^c ; Chad Constance^c ; Kasey Hill^c ; Walt A. Shaw^c ; Fé ; lix M. Goñ ; i^a ; Alicia Alonso^a ; ^{alicia.alonso@ehu.es" class="auth_mail}
关键词：DMPC ; (1 ; 2-dimyristoyl-sn-glycero-3-phosphocholine) ; 1H-NMR ; (proton nuclear magnetic resonance) ; LDL ; (low density lipoprotein) ; Liss Rho PE ; (Lissamine Rhodamine B phosphatidyl ethanolamine) ; PAPC ; (1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine) ; PA ; (phosphatidic acid) ; PC ; (phosphatidyl choline) ; PE ; (phosphatidyl ethanolamine) ; PI ; (phosphatidyl inositol) ; 31P-NMR ; (phosphorous 31 Nuclear Magnetic Resonance) ; SM ; (sphingomyelin) ; Top Fluor Cer1P ; (Top Fluor ceramides-1-phosphate)
刊名：Biochimica et Biophysica Acta (BBA)/Biomembranes
出版年：August 2014
年：2014
卷：1838
期：8
页码：2071-2077
全文大小：715 K

文摘

•: Lipid peroxidation plays a central role in the pathogenesis of atherosclerosis.
•: We have analyzed the interaction of sphingosine with peroxidized bilayers.
•: Sphingosine causes aggregation of Cu^2 +-peroxidized vesicles.
•: Aggregation is facilitated by negatively-charged phospholipids in the membrane.
•: Formation of imines in the membrane appeared to be necessary for aggregation.

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.