Methicillin-resistant food-related Staphylococcus aureus: a review of current knowledge and biofilm formation for future studies and applications

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• 作者：Agapi I. Doulgeraki^a ; ^{adoulgeraki@aua.gr} ; Pierluigi Di Ciccio^b ; Adriana Ianieri^b ; George-John E. Nychas^a
• 关键词：Staphylococcus aureus ; MRSA ; Biofilm ; Quorum sensing ; Virulence
• 刊名：Research in Microbiology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：168
• 期：1
• 页码：1-15
• 全文大小：681 K
• 卷排序：168

文摘

There is increasing concern about the public health impact of methicillin-resistant Staphylococcus aureus. Food and animal are vectors of transmission, but the contribution of a contaminated environment is not well characterized. With regard to this, staphylococcal biofilms serve as a virulence factor, allowing MRSA strains to adhere to surfaces and other materials used in the food industry.Methicillin resistance and biofilm-forming capacity may contribute to the success of S. aureus as a human pathogen in both health care and community settings and the food production chain. This review summarizes current knowledge about the significance of food- and animal-derived MRSA strains and provides data on attachment and biofilm formation of MRSA. In addition, the impact of quorum sensing on MRSA gene expression and biofilm formation is examined.