Parkinson’s disease-associated GPR37 receptor regulates cocaine-mediated synaptic depression in corticostriatal synapses

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• 作者：Daniel Rial^a ; Xavier Morató ; ^b ; ^c ; Joana I. Real^a ; Francisco Q. Gonç ; alves^a ; Igor Stagljar^d ; Frederico C. Pereira^e ; Ví ; ctor Ferná ; ndez-Dueñ ; as^b ; ^c ; Rodrigo A. Cunha^a ; ^e ; Francisco Ciruela^b ; ^c ; ^{fciruela@ub.edu}
• 关键词：GPR37 ; Synaptic plasticity ; Cocaine ; Orphan receptor
• 刊名：Neuroscience Letters
• 出版年：2017
• 出版时间：18 January 2017
• 年：2017
• 卷：638
• 期：Complete
• 页码：162-166
• 全文大小：1044 K
• 卷排序：638

文摘

A potential role GPR37 in corticostriatal synaptic transmission is proposed. GPR37 genetic deletion does not modify synaptic transmission and short-term plasticity. GPR37 regulates cocaine-mediated synaptic depression in corticostriatal synapses.