MD-1 deficiency attenuates dextran sodium sulfate (DSS)-induced colitis through modulating the function of colonic lamina propria dendritic cells

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

MD-1 deficiency attenuates dextran sodium sulfate (DSS)-induced colitis through modulating the function of colonic lamina propria dendritic cells

详细信息查看全文

作者：Huaqin Pan^a ; ^b ; ¹ ; ^{phq2012@whu.edu.cnv" class="auth_mail" title="E-mail the corresponding author} ; ^{panhuaqin2004@sina.com" class="auth_mail" title="E-mail the corresponding author} ; Guqin Zhang^c ; ¹ ; ^{zgqxiaoxiao@126.com" class="auth_mail" title="E-mail the corresponding author} ; Lin Zhang^a ; ^b ; ^{zhanglin19910528@163.com" class="auth_mail" title="E-mail the corresponding author} ; Wei Wang^a ; ^b ; ^{weiwang0303@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Jian Shang^a ; ^b ; ^{shangjian1988@126.com" class="auth_mail" title="E-mail the corresponding author} ; Xiaobing Wang^a ; ^b ; ^{wxbandzhp@163.com" class="auth_mail" title="E-mail the corresponding author} ; Qiu Zhao^a ; ^b ; ^{zhaoqiu@medmail.com.cn" class="auth_mail" title="E-mail the corresponding author} ; Jin Li^a ; ^b ; ^{lijinluyi@aliyun.com" class="auth_mail" title="E-mail the corresponding author}
关键词：MD-1 ; Colitis ; Dendritic cells ; Dextran sodium sulfate
刊名：Molecular Immunology
出版年：2016
出版时间：July 2016
年：2016
卷：75
期：Complete
页码：1-10
全文大小：2923 K

文摘

•: Elevated MD-1 mRNA is found in the colon of IBD patients and diseased mice.
•: MD-1^−/− mice are protected against DSS-induced colitis characterized by decreased colonic inflammatory gene expression and infiltration of colonic inflammatory cells.
•: MD-1^−/− mice do not alter intestinal permeability after DSS treatment.
•: MD-1 deficiency modulates the function of colonic lamina propria DCs (LPDCs).

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.