Ptbp1 and Exosc9 knockdowns trigger skin stability defects through different pathways

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Ptbp1 and Exosc9 knockdowns trigger skin stability defects through different pathways

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作者：Maud Noiret ; Sté ; phanie Mottier ; Gaelle Angrand ; Carole Gautier-Courteille ; Hubert Lerivray ; Justine Viet ; Luc Paillard ; Agnes Mereau ; Serge Hardy ; Yann Audic ; ^{yann.audic@univ-rennes1.fr" class="auth_mail" title="E-mail the corresponding author}
关键词：RNA-binding proteins ; Genodermatosis ; Post-transcriptional regulations ; Epidermis
刊名：Developmental Biology
出版年：2016
出版时间：15 January 2016
年：2016
卷：409
期：2
页码：489-501
全文大小：4309 K

文摘

•: Exosc9 and ptbp1 knockdown triggers blister development in the dorsalepidermis.
•: Multiciliated cell development is compromised in Exosc9 morphants.
•: Embryos depleted in Ptbp1 and Exosc9 display phenotypically different skin defects.
•: Ptbp1 and Exosc9 differentially control expression of genodermatosis-related genes.

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