Perturbation of the Warburg effect increases the sensitivity of cancer cells to TRAIL-induced cell death

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Perturbation of the Warburg effect increases the sensitivity of cancer cells to TRAIL-induced cell death

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作者：Minami Kumazaki ; ^{t3501001@edu.gifu-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Haruka Shinohara ; Kohei Taniguchi ; Tomoaki Takai ; Yuki Kuranaga ; Nobuhiko Sugito ; Yukihiro Akao
关键词：TRAIL-induced apoptosis ; Warburg effect ; SiR-PTBP1 ; CCN1
刊名：Experimental Cell Research
出版年：2016
出版时间：10 September 2016
年：2016
卷：347
期：1
页码：133-142
全文大小：2324 K

文摘

•: Warburg effect was closely associated with the TRAIL-induced apoptosis.
•: Silencing of Warburg effect-related PTBP1 increased sensitivity to the apoptosis.
•: PTBP1 could be used as a possible target molecule to conquer the resistance to TRAIL.

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