Expression of Cryptosporidium parvum thioredoxin peroxidase in COS-7 cells confers radioprotection

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Expression of Cryptosporidium parvum thioredoxin peroxidase in COS-7 cells confers radioprotection

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作者：Semie Hong^a ; ¹ ; Jae-Hwan Kim^b ; ¹ ; Sejoung Yoon^b ; Kyoungjin Kim^b ; Seobo Sim^b ; Woo-Yoon Park^c ; Jae-Ran Yu^b ; ^{maria205@kku.ac.kr" class="auth_mail" title="E-mail the corresponding author}
关键词：Cryptosporidium parvum ; Thioredoxin peroxidase ; Radioprotection
刊名：Experimental Parasitology
出版年：2016
出版时间：April 2016
年：2016
卷：163
期：Complete
页码：8-15
全文大小：1538 K

文摘

•: CpTPx was transfected to COS-7 cells.
•: CpTPx mediated higher cell survival rates among the experimental groups.
•: Potent antioxidant and DNA damage protection activity of CpTPx are conserved in cells.
•: Apoptotic change was reduced in CpTPx transfected COS-7 after irradiation.
•: Transfected CpTPx contribute to radioprotection in COS-7 cells.

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