RELMs in the Realm of Helminths

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• 作者：William G.C. Horsnell¹ ; ^{wghorsnell@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Benjamin G. Dewals²
• 刊名：Trends in Parasitology
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：32
• 期：7
• 页码：512-514
• 全文大小：642 K

文摘

Resistin-like molecule (RELM) proteins are essential for immunity to helminths. Recently, Chen and collaborators identified a dominant role for RELMα over RELMβ in host immunity to Nippostrongylus brasiliensis using a double knockout system. The study highlighted how important and yet divergent the contributions of these proteins are in the control of helminth infections.