Seroepidemiology of BVDV-1, BoHV-1, BRSV and BPIV-3 and risk of BRD was investigated.
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For each virus, being seronegative at entry increased risk of BRD in feedlot cattle.
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Animals seronegative for more than one virus were at progressively increased risk.
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For each virus seroincrease resulted in increased risk of BRD in feedlot cattle.
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Seroincrease for more than one virus further increased risk of BRD.
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