Fatty acid synthase plays a positive role in shrimp immune responses against Vibrio parahaemolyticus infection

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• 作者：Hongliang Zuo^a ; ^b ; ^c ; ^d ; ¹ ; Jiefeng Gao^a ; ^b ; ¹ ; Jia Yuan^a ; ^b ; Hengwei Deng^a ; ^b ; Linwei Yang^a ; ^b ; Shaoping Weng^a ; ^b ; Jianguo He^a ; ^b ; ^c ; ^d ; ^{lsshjg@mail.sysu.edu.cn} ; Xiaopeng Xu^a ; ^b ; ^c ; ^d ; ^{xuxpeng@mail.sysu.edu.cn}
• 关键词：Fatty acid synthase ; Litopenaeus vannamei ; Immune responses ; Vibrio parahaemolyticus ; Bacterial infection
• 刊名：Fish & Shellfish Immunology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：60
• 期：Complete
• 页码：282-288
• 全文大小：1669 K
• 卷排序：60

文摘

Expression of LvFAS is up-regulated during V. parahaemolyticus infection. The promoter of LvFAS is regulated by NF-κB family proteins. Knockdown of LvFAS increases the mortality of V. parahaemolyticus infected shrimp. LvFAS influences expression of multiple immune-responsive genes.