Silver nanoparticles synthesized using Taxus extracts displayed potent anticancer activity on cancer cell lines.

Aqueous extract synthesized nanoparticles represented far less toxicity on normal human fibroblast cells.

Silver nanoparticles apparently induced DNA damage depending on concentration and exposure time.

Treatment of cancer cells with silver nanoparticles considerably induced the expression of apoptosis related genes.

Flow cytometric analysis revealed a combination of apoptosis and necrosis after nanoparticle treatment.