文摘
The myenteric plexus and the submucosal plexus make up the enteric nervous system (ENS), and control intestinal motility, local perfusion and physiologic function. Local inflammation of the myenteric plexus, by lymphocytic or eosinophilic cells is associated with intestinal pseudo-obstruction. We describe the youngest reported case of eosinophilic myenteric ganglionitis (EMG), and the only reported case of EMG occurring with Hirschsprung's disease (HD). Recently, a term male neonate under our care failed to pass meconium and was diagnosed with both EMG and HD. He was treated with fecal diversion and dietary modification. He did not require anti-inflammatory medical therapy. He subsequently underwent resection of the colonic segment affected by HD, and his EMG resolved with dietary modification by the time of ostomy takedown. He continues to tolerate a regular pediatric diet, meets normal growth milestones, and requires no maintenance anti-inflammatory therapy for EMG.
