Glycyrrhizin ameliorates oxidative stress and inflammation in hippocampus and olfactory bulb in lithium/pilocarpine-induced status epilepticus in rats

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Glycyrrhizin ameliorates oxidative stress and inflammation in hippocampus and olfactory bulb in lithium/pilocarpine-induced status epilepticus in rats

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作者：Susana Gonz&aacute ; lez-Reyes^a ; Juan Jair Santill&aacute ; n-Cigales^a ; Angé ; lica Saraí ; Jimé ; nez-Osorio^b ; José ; Pedraza-Chaverri^b ; Rosalinda Guevara-Guzm&aacute ; n^a ; ^{rguevara@unam.mx" class="auth_mail" title="E-mail the corresponding author}
关键词：Status epilepticus ; Inflammation ; Oxidative stress ; Hippocampus ; Olfactory bulb ; Glycyrrhizin
刊名：Epilepsy Research
出版年：2016
出版时间：October 2016
年：2016
卷：126
期：Complete
页码：126-133
全文大小：1352 K

文摘

•: GL prevents oxidative stress after status epilepticus in the hippocampus and olfactory bulb.
•: Pretreatment with GL increases antioxidant enzyme activity in the hippocampus.
•: GL preserves enzyme activities in the olfactory bulb.
•: GL decreases inflammation in the hippocampus and olfactory bulb after status epilepticus.