Sex differences in the development of neuroanatomical functional connectivity underlying intelligence found using Bayesian connectivity analysis

详细信息    查看全文

• 作者：Vincent J. Schmithorst ; Scott K. Holl
• 刊名：NeuroImage
• 出版年：2007
• 出版时间：March 2007
• 年：2007
• 卷：35
• 期：1
• 页码：406-419
• 全文大小：1692 K

文摘

A Bayesian method for functional connectivity analysis was adapted to investigate between-group differences. This method was applied in a large cohort of almost 300 children to investigate differences in boys and girls in the relationship between intelligence and functional connectivity for the task of narrative comprehension. For boys, a greater association was shown between intelligence and the functional connectivity linking Broca's area to auditory processing areas, including Wernicke's areas and the right posterior superior temporal gyrus. For girls, a greater association was shown between intelligence and the functional connectivity linking the left posterior superior temporal gyrus to Wernicke's areas bilaterally. A developmental effect was also seen, with girls displaying a positive correlation with age in the association between intelligence and the functional connectivity linking the right posterior superior temporal gyrus to Wernicke's areas bilaterally. Our results demonstrate a sexual dimorphism in the relationship of functional connectivity to intelligence in children and an increasing reliance on inter-hemispheric connectivity in girls with age.