Modigraf Administration Through Jejunostomy in Liver Transplant Recipient: Case Report

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• 作者：V. Camacho Marente ; L.M. Marin Gomez ; J. Gracia Martinez ; C. Bernal-Bellido ; G. Su谩rez-Artacho ; J.M. 脕lamo-Mart铆nez ; L. Barrera-Pulido ; J. Serrano-D铆az-Canedo ; F.J. Padillo-Ruiz ; M.A. G贸mez-Bravo
• 刊名：Transplantation Proceedings
• 出版年：December, 2013
• 年：2013
• 卷：45
• 期：10
• 页码：3670-3671
• 全文大小：384 K

文摘

We report our experience with a 61-year-old patient with alcoholic and hepatitis C cirrhosis who underwent liver transplantation. On the 3rd postoperative day he presented a mediastinitis secondary to esophageal perforation produced by a Linton tube. An esophagectomy with jejunostomy was performed. Tacrolimus granules for oral suspension (Modigraf) were administered through the jejunostomy. This case report highlights the use of Modigraf and the absence of secondary effects. We observed biochemical parameters during the jejunostomy period. We discuss the administration strategy applied and whether tacrolimus granules for oral suspension by jejunostomy affect the bioavailability and its side effects.