Tuberculosis-diabetes co-morbidity is characterized by heightened systemic levels of circulating angiogenic factors

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• 作者：Nathella Pavan Kumar^a ; Kadar Moideen^a ; Shanmugam Sivakumar^a ; Pradeep A. Menon^a ; Vijay Viswanathan^b ; Hardy Kornfeld^c ; Subash Babu^a ; ^d ; ^{sbabu@mail.nih.gov}
• 关键词：Tuberculosis ; Diabetes ; Angiogenesis ; Biomarkers
• 刊名：Journal of Infection
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：74
• 期：1
• 页码：10-21
• 全文大小：2062 K
• 卷排序：74

文摘

Angiogenic factors are associated with disease severity and adverse clinical presentation in TB-DM. The systemic increase in angiogenic factor levels is driven by dysglycemia and bacterial burdens. Treatment results in reversal of enhanced levels of systemic angiogenic factors.