Catecholaminergic neurons in synaptic connections with pre-Bötzinger complex neurons in the rostral ventrolateral medulla in normoxic and daily acute intermittent hypoxic rats

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Catecholaminergic neurons in synaptic connections with pre-Bötzinger complex neurons in the rostral ventrolateral medulla in normoxic and daily acute intermittent hypoxic rats

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作者：Jun-Jun Kang^a ; Wei-Hua Liang^b ; Chun-Sing Lam^c ; Xiao-Feng Huang^b ; Shou-Jing Yang^b ; Margaret T.T. Wong-Riley^d ; Man-Lung Fung^c ; ^{fungml@hku.hk" class="auth_mail" title="E-mail the corresponding author} ; Ying-Ying Liu^a ; ^{yingyliu@fmmu.edu.cn" class="auth_mail" title="E-mail the corresponding author}
关键词：CVLM ; caudal ventrolateral medulla ; dAIH ; daily acute intermittent hypoxia ; DβH ; dopamine-β-hydroxylase ; 5-HT2AR ; 5-hydroxytryptamine 2A receptor ; ir ; immunoreactive ; IVLM ; intermediate ventrolateral medulla ; LTF ; long-term facilitation ; NK1R ; neurokinin 1 receptor ; PNMT ; phenylethanolamine N-methyl transferase ; PB ; phosphate buffer ; PBS ; phosphate buffered saline ; pre-Bö ; tC ; pre-Bö ; tzinger complex ; PKC ; protein kinase C ; RVLM ; rostral ventrolateral medulla
刊名：Experimental Neurology
出版年：2017
出版时间：January 2017
年：2017
卷：287
期：part_P2
页码：165-175
全文大小：3061 K

文摘

•: DβH-ir terminals form asymmetric synapses with NK1R-ir neurons in the pre-BötC.
•: dAIH induces an increase in DβH expression in the pre-BötC.
•: dAIH evokes increases in the number and area of NK1R-ir processes in the pre-BötC.
•: Close appositions of DβH- and NK1R-ir profiles are significantly elevated in the pre-BötC after dAIH exposure.