A comparison of neurometabolites between remitted bipolar disorder and depressed bipolar disorder: A proton magnetic resonance spectroscopy study

详细信息    查看全文

• 作者：Tao Liu^a ; ^b ; Ying Wang^a ; Shuming Zhong^a ; Bing Wang^c ; Xiaoxiao Liao^a ; Shunkai Lai^a ; Yanbin Jia^a ; ^{Yanbinjia2006@163.com}
• 关键词：Remitted bipolar disorder ; Depressed bipolar disorder ; Neurometabolite ; Proton magnetic resonance spectroscopy
• 刊名：Journal of Affective Disorders
• 出版年：2017
• 出版时间：15 March 2017
• 年：2017
• 卷：211
• 期：Complete
• 页码：153-161
• 全文大小：586 K
• 卷排序：211

文摘

We compared neurometabolites between remitted and depressed bipolar disorder (BD) patients by using proton magnetic resonance spectroscopy. We computed correlation coefficients between abnormal neurometabolites and clinical data in BD patients. We chose prefrontal whiter matter (PWM), thalamus and putamen as the volume of interest to be measured neurometabolites. The higher PWM N-acetylaspartate/Creatine ratios were found in remitted BD and controls than depressed BD patients. The correlations between abnormal N-acetylaspartate/Creatine ratios and clinical data in BD patients were also found.