Inhibition of junctional adhesion molecule-A/LFA interaction attenuates leukocyte trafficking and inflammation in brain ischemia/reperfusion injury

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Opening Hours
Collections
Help Via Email

Electronic Information Resources

Inhibition of junctional adhesion molecule-A/LFA interaction attenuates leukocyte trafficking and inflammation in brain ischemia/reperfusion injury

详细信息查看全文

作者：Nikola Sladojevic^a ; Svetlana M. Stamatovic^a ; Richard F. Keep^b ; ^c ; Jamison J. Grailer^a ; J. Vidya Sarma^a ; Peter A. Ward^a ; Anuska V. Andjelkovic^a ; ^b ; ^{anuskaa@med.umich.edu" class="auth_mail}
关键词：Tight junctions ; JAM-A ; Stroke ; Inflammation ; Blood&ndash ; brain barrier
刊名：Neurobiology of Disease
出版年：July 2014
年：2014
卷：67
期：Complete
页码：57-70
全文大小：1896 K

文摘

•: We examine the effect of modulation of JAM-A function in treatment of MCAO in mice.
•: We designed small peptide inhibitor for targeting JAM-A.
•: JAM-A inhibition reduces total infarct volumes.
•: JAM-A inhibition reduced number of infiltrating leukocytes and inflammatory response.

NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via email.