Nicotine stabilization in composite sodium alginate based wafers and films for nicotine replacement therapy

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Nicotine stabilization in composite sodium alginate based wafers and films for nicotine replacement therapy

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作者：Obinna C. Okeke ; Joshua S. Boateng ; ^{J.S.Boateng@gre.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; ^{joshboat40@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; ^{joshboat@hotmail.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Gelatine ; Glycerol ; Hydroxypropylmethylcellulose ; Magnessium aluminium silicate ; Mucin ; Nicotine ; Potassium dihydrogen phosphate ; Sodium acetate ; Sodium alginate ; Trimethylamine
刊名：Carbohydrate Polymers
出版年：2017
出版时间：2 January 2017
年：2017
卷：155
期：Complete
页码：78-88
全文大小：1838 K

文摘

⿢: Nicotine has been loaded into composite sodium alginate based films and wafers for nicotine replacement therapy (NRT).
⿢: Magnesium aluminium silicate and sodium alginate helped stabilise the nicotine within the formulations and enhanced drug recovery.
⿢: The films and wafers showed different physical properties which affected their functional characteristics for an ideal buccal NRT.

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