Classic cadherin expressions balance postnatal neuronal positioning and dendrite dynamics to elaborate the specific cytoarchitecture of the mouse cortical area

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Classic cadherin expressions balance postnatal neuronal positioning and dendrite dynamics to elaborate the specific cytoarchitecture of the mouse cortical area

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作者：Saki F. Egusa^a ; ^b ; ^{segusa@ncnp.go.jp" class="auth_mail" title="E-mail the corresponding author} ; Yukiko U. Inoue^a ; ^{yinn3@ncnp.go.jp" class="auth_mail" title="E-mail the corresponding author} ; Junko Asami^a ; ^{asami@ncnp.go.jp" class="auth_mail" title="E-mail the corresponding author} ; Youhei W. Terakawa^a ; ^c ; ^{y_tera@gifu-u.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Mikio Hoshino^a ; ^{hoshino@ncnp.go.jp" class="auth_mail" title="E-mail the corresponding author} ; Takayoshi Inoue^a ; ^{tinoue@ncnp.go.jp" class="auth_mail" title="E-mail the corresponding author}
关键词：Classic cadherins ; Cortical arealization ; In utero electroporation ; Somatosensory barrel ; Neuronal activity dependent regulation
刊名：Neuroscience Research
出版年：2016
出版时间：April 2016
年：2016
卷：105
期：Complete
页码：49-64
全文大小：9434 K

文摘

•: We confirm expression profiles of classic cadherins in the mouse barrel cortex.
•: We generate a resourceful transgenic mouse illuminating nuclei of barrel neurons.
•: A conditional electroporation method allows us to test postnatal roles of cadherins.
•: Cadherins are involved in elaboration of the barrel area specific cytoarchitecture.
•: Activity dependent machinery might modulate the cadherin expression profiles.