Altered intrinsic properties and bursting activities of neurons in layer IV of somatosensory cortex from Fmr-1 knockout mice

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Altered intrinsic properties and bursting activities of neurons in layer IV of somatosensory cortex from Fmr-1 knockout mice

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作者：Linming Zhang^a ; ^b ; ^c ; Zhanrong Liang^a ; ^b ; Pingping Zhu^a ; ^b ; Meng Li^a ; ^b ; Yong-Hong Yi^a ; ^b ; Wei-Ping Liao^a ; ^b ; Tao Su^a ; ^b ; ^{su@gzneurosci.com" class="auth_mail" title="E-mail the corresponding author}
关键词：Fragile X syndrome ; Excitability ; Firing pattern ; Intrinsic membrane properties ; Epilepsy
刊名：Experimental Neurology
出版年：2016
出版时间：June 2016
年：2016
卷：280
期：Complete
页码：60-69
全文大小：1153 K

文摘

•: Neurons from Fmr-1 KO barrel cortex tend to burst firing.
•: Altered intrinsic properties facilitate discharges in Fmr-1 KO neurons.
•: Increased burst activities in epileptiform conditions

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