An Arp2/3 Nucleated F-Actin Shell Fragments Nuclear Membranes at Nuclear Envelope Breakdown in Starfish Oocytes

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An Arp2/3 Nucleated F-Actin Shell Fragments Nuclear Membranes at Nuclear Envelope Breakdown in Starfish Oocytes

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作者：Masashi Mori¹ ; Ká ; lmá ; n Somogyi¹ ; Hiroshi Kondo¹ ; Nilah Monnier³ ; ⁴ ; Henning J. Falk¹ ; Pedro Machado² ; Mark Bathe³ ; ⁵ ; Franç ; ois Né ; dé ; lec¹ ; Pé ; ter Lé ; ná ; rt¹ ; ^{lenart@embl.de" class="auth_mail}
刊名：Current Biology
出版年：16 June 2014
年：2014
卷：24
期：12
页码：1421-1428
全文大小：5028 K

文摘

•: An F-actin “shell” assembles underneath the nuclear envelope at NEBD in oocytes
•: This transient F-actin shell is nucleated by the Arp2/3 complex
•: The F-actin shell functions to fragment nuclear membranes in NEBD
•: Prevention of F-actin shell formation in meiosis leads to formation of aneuploid eggs

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