Investigation of the metabolites of the HIF stabilizer FG-4592 (roxadustat) in five different in vitro models and in a human doping control sample using high resolution mass spectrometry
刊名:Journal of Pharmaceutical and Biomedical Analysis
出版年:2017
出版时间:5 February 2017
年:2017
卷:134
期:Complete
页码:228-236
全文大小:1176 K
卷排序:134
文摘
Metabolites from the HIF stabilizer FG-4592 were investigated. Five in vitro methods and a human doping control sample were used as models. Twelve different metabolites were detected using UHPLC-QTOF-MS. Three of the in vitro models had one metabolite in common.
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