Karyotypic abnormalities associated with Epstein-Barr virus status in classical Hodgkin lymphoma

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Karyotypic abnormalities associated with Epstein-Barr virus status in classical Hodgkin lymphoma

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作者：Nathan D. Montgomery^a ; ^{nathan.montgomery@unchealth.unc.edu" class="auth_mail" title="E-mail the corresponding author} ; Wilborn B. Coward IV^b ; Steven Johnson^a ; Ji Yuan^c ; Margaret L. Gulley^a ; Stephanie P. Mathews^a ; Kathleen Kaiser-Rogers^a ; ^d ; Kathleen W. Rao^a ; ^d ; Warren G. Sanger^e ; Jennifer N. Sanmann^e ; ¹ ; Yuri Fedoriw^a ; ¹
关键词：Classical Hodgkin lymphoma ; Epstein&ndash ; Barr virus ; karyotype ; genomic instability
刊名：Cancer Genetics
出版年：2016
出版时间：September 2016
年：2016
卷：209
期：9
页码：408-416
全文大小：1609 K

文摘

•: EBV-negative cases of CHL are characterized by increased karyotypic complexity.
•: Cytogenetic features associated with CHL histologic subtype are also reported.
•: The effect of EBV may be driven by a subset of cases with relatively simple karyotypes.

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