Montanide IMS 1312 VG adjuvant enhances the efficacy of immersion vaccine of inactivated viral hemorrhagic septicemia virus (VHSV) in olive flounder, Paralichthys olivaceus

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• 作者：Jee Youn Hwang^a ; ^{jinihwang@korea.kr} ; Mun-Gyeong Kwon^a ; ^{mgkwon@korea.kr} ; Yu Jin Kim^a ; ^{yujinie4@gmail.com} ; Sung-Hee Jung^b ; ^{immu@korea.kr} ; Myoung-Ae Park^c ; ^{mgpark@korea.kr} ; Maeng-Hyun Son^a ; ^{hyu782@korea.kr}
• 关键词：Viral hemorrhagic septicemia virus ; Olive flounder ; Paralichthys olivaceus ; Immersion vaccine ; Adjuvant
• 刊名：Fish & Shellfish Immunology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：60
• 期：Complete
• 页码：420-425
• 全文大小：670 K
• 卷排序：60

文摘

Immersion vaccination of heat-inactivated VHSV with Montanide 1312 VG protected olive flounder from VHS. Immersion vaccination inceased the levels of several immune genes. Addition of Montanide 1312 VG further increased the levels of immune genes. Duration of protective effect of immersion vaccination was short.