Two cases of pseudo-achalasia with lung cancer: Case report and short literature review

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• 作者：Taizou Hirano ; M.D. ; Ph.D.^a ; ^{taizou2001@gmail.com} ; Eisaku Miyauchi^a ; ^{miyauchi@rm.med.tohoku.ac.jp} ; Akira Inoue^b ; ^{akinoue@idac.tohoku.ac.jp} ; Ryotaro Igusa^c ; ^{ryo-igusa@h-osaki.jp} ; Shigeki Chiba^a ; ^{shi-chiba@rm.med.tohoku.ac.jp} ; Kazuhiro Sakamoto^d ; ^{ksakamoto-och@h-osaki.jp} ; Hisatoshi Sugiura^a ; ^{sugiura@rm.med.tohoku.ac.jp} ; Toshiaki Kikuchi^e ; ^{kikuchi@med.niigata-u.ac.jp} ; Masakazu Ichinose^a ; ^{ichinose@rm.med.tohoku.ac.jp}
• 关键词：Lung cancer ; Pseudo-achalasia ; Secondary achalasia ; Paraneoplastic neurological syndromes
• 刊名：Respiratory Investigation
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：54
• 期：6
• 页码：494-499
• 全文大小：1906 K
• 卷排序：54

文摘

Pseudo-achalasia with lung cancer is a rare complication. We present 2 cases of pseudo-achalasia with lung cancer and summarize previous reports. The previous reports suggested that lung cancer can be complicated with pseudo-achalasia caused by paraneoplastic neurological syndromes rather than direct invasion of the tumor cells to the lower esophageal sphincter, irrespective of the histology of the lung cancer; this can strongly influence the performance status. Treatment for pseudo-achalasia improves not only the symptoms, but also the performance status. Therefore, pseudo-achalasia should be considered when lung cancer patients present with dysphagia without other known causes.