Recommendations for Successful Training on Methods of Delivery of Biologics for Cardiac Regeneration: A Report of the International Society for Cardiovascular Translational Research

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• 作者：Nabil Dib ; MD ; MSc ; ^{ndib@cardiostem.com} ; Philippe Menasche ; MD ; PhD ; Jozef J. Bartunek ; MD ; PhD ; Andreas M. Zeiher ; MD ; Andre Terzic ; MD ; PhD ; Nicolas A. Chronos ; MD ; Timothy D. Henry ; MD ; Nicholas S. Peters ; MD ; PhD ; Francisco Ferná ; ndez-Avilé ; s ; MD ; PhD ; Magdi Yacoub ; MD ; PhD ; Timothy A. Sanborn ; MD ; Anthony DeMaria ; MD ; Richard A. Schatz ; MD ; Doris A. Taylor ; PhD ; Shmuel Fuchs ; MD ; Silviu Itescu ; MD ; Leslie W. Miller ; MD ; Jonathan H. Dinsmore ; PhD ; George D. Dangas ; MD ; PhD ; Jeffrey J. Popma ; MD ; Jennifer L. Hall ; PhD ; David R. Holmes Jr ; MD
• 关键词：myocardial regeneration ; stem cells ; training ; injection ; catheter
• 刊名：JACC: Cardiovascular Interventions
• 出版年：2010
• 出版时间：March 2010
• 年：2010
• 卷：3
• 期：3
• 页码：265-275
• 全文大小：1715 K

文摘

The field of myocardial regeneration (angiogenesis and myogenesis) might prove to play an important role in the future management of cardiovascular disease. Stem cells are currently undergoing testing in Phase I and Phase II clinical trials. Methods of delivery will affect the outcome of such therapies, perhaps significantly. This document provides suggested guidance in 4 methods of delivery: endocardial, intracoronary, coronary sinus, and epicardial.