Reprint of: Acute Graft-versus-Host Disease: Novel Biological Insights

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Reprint of: Acute Graft-versus-Host Disease: Novel Biological Insights

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作者：Takanori Teshima¹ ; ^{teshima@med.hokudai.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Pavan Reddy² ; Robert Zeiser³
关键词：Graft-versus-host disease ; Intestinal stem cells ; Paneth cells ; Histone deacetylase ; Butyrate ; Janus kinase ; Ruxolitinib
刊名：Biology of Blood and Marrow Transplantation
出版年：2016
出版时间：March 2016
年：2016
卷：22
期：3_supp_S
页码：S3-S8
全文大小：565 K

文摘

•: Intestinal stem cells and their niche Paneth cells are targeted in graft-versus-host disease.
•: There is an interplay between graft-versus-host disease and intestinal microbiota and metabolome.
•: JAK-STAT pathways are required for responses to multiple cytokines and represent potential new targets in graft-versus-host disease.

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