Screening of dioxin-like compounds by complementary evaluation strategy utilising ELISA, micro-EROD, and HRGC-HRMS in soil and sediments from Montevideo, Uruguay

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Screening of dioxin-like compounds by complementary evaluation strategy utilising ELISA, micro-EROD, and HRGC-HRMS in soil and sediments from Montevideo, Uruguay

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作者：W. Levy^a ; ^{walkiria.levy@helmholtz-muenchen.de" class="auth_mail} ; B.M. Brena^b ; ^c ; ^{bbrena@fq.edu.uy" class="auth_mail} ; B. Henkelmann^a ; S. Bernhö ; ft^a ; M. Pirez^d ; G. Gonzá ; lez-Sapienza^d ; ^{ggonzal@fq.edu.uy" class="auth_mail} ; K.-W. Schramm^a ; ^e ; ^{schramm@helmholtz-muenchen.de" class="auth_mail}
关键词：PCDD ; polychlorinated dibenzo-p-dioxins ; PCDF ; polychlorinated dibenzofurans ; PCB ; polychlorinated biphenyls ; PAH ; polycyclic aromatic hydrocarbons ; HRGC/HRMS ; high resolution gas chromatography and high resolution mass spectrometry ; DMEM ; Dulbecco&rsquo ; s Minimum Essential Medium ; TCDD ; 2 ; 3 ; 7 ; 8-tetrachlorodibenzo-p-dioxin ; TE values ; TCDD toxicity equivalent values ; TMDD ; 2 ; 3 ; 7-trichloro-8-methyl-dibenzo-p-dioxin ; BSA ; bovine serum albumin ; PBS ; phosphate buffer solution ; PBST ; phosphate buffer
刊名：Toxicology in Vitro
出版年：August 2014
年：2014
卷：28
期：5
页码：1036-1045
全文大小：1864 K

文摘

•: Bioassays (EROD and ELISA) and analytical results were highly correlated.
•: Cut-off values of 220 (ELISA) and 330 (EROD) ng TCDD equivalents/kg dry soil were proposed.
•: The bioassays are suggested as an alternative tool for first screening and monitoring.