Revealing the complex effects of salinity on copper toxicity in an estuarine clam Potamocorbula laevis with a toxicokinetic-toxicodynamic model

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• 作者：Wen-Qian Chen^a ; Wen-Xiong Wang^a ; ^b ; ^c ; Qiao-Guo Tan^a ; ^b ; ^{tanqg@xmu.edu.cn}
• 关键词：Toxicokinetics ; Toxicodynamics ; Cu ; Salinity ; Biotic ligand model
• 刊名：Environmental Pollution
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：222
• 期：Complete
• 页码：323-330
• 全文大小：656 K
• 卷排序：222

文摘

The geochemical effects of elevated salinity decrease Cu bioaccumulation. The physiological effects of elevated salinity increase Cu toxicity. A toxicokinetic-toxicodynamic (TK-TD) model is developed to quantify the dual effects of salinity. The biotic ligand model can be integrated into the TD-TK model for predicting salinity effects.