The underlying mechanisms of genetic innovation and speciation in the family Corynebacteriaceae: A phylogenomics approach

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• 作者：Xiao-Yang Zhi^a ; ^b ; ^{xyzhi@ynu.edu.cn} ; Zhao Jiang^a ; Ling-Ling Yang^a ; Ying Huang^b
• 关键词：Corynebacteriaceae ; Genetic innovation ; Speciation ; Horizontal gene transfer ; Gene loss ; Phylogenomics
• 刊名：Molecular Phylogenetics and Evolution
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：107
• 期：Complete
• 页码：246-255
• 全文大小：2047 K
• 卷排序：107

文摘

We analyzed the pan-genome of family Corynebacteriaceae. Gene loss has been the primary force causing genetic changes. Genetic changes mainly affected transporters, TCS, and amino acids metabolisms. HGT introduced not only the pathogenicity, but also the antimicrobial resistance. Dispersive HGT/gene loss caused the inconsistent of supermatrix and gene content phylogenies.