A flexible-dose dispenser for immediate and extended release 3D printed tablets

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A flexible-dose dispenser for immediate and extended release 3D printed tablets

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作者：Katarzyna Pietrzak^a ; ^b ; Abdullah Isreb^a ; Mohamed A. Alhnan^a ; ^{MAlbedAlhnan@uclan.ac.uk" class="auth_mail" title="E-mail the corresponding author}
关键词：DSC ; Differential Scanning Calorimetry ; FDM ; Fused Deposition Modelling ; FFF ; Fused filament fabrication ; SEM ; Scanning Electron Microscopy ; HME ; Hot Melt Extrusion ; HPC ; hydroxypropyl cellulose ; PVA ; polyvinyl alcohol ; TEC ; triethyl citrate ; TGA ; Thermo Gravimetrical Analysis ; USP ; United States Pharmacopeia
刊名：European Journal of Pharmaceutics and Biopharmaceutics
出版年：2015
出版时间：October 2015
年：2015
卷：96
期：Complete
页码：380-387
全文大小：2467 K

文摘

•: The method bridges the affordable and digitally controlled Fused Deposition Modelling (FDM) 3D printing with HME.
•: First report for applying this type of 3D printing to a widely used methacrylic and cellulose based polymers.
•: A realistic drug loading using a challenging easy-to-swallow tablet design.

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