Identification of a novel class B scavenger receptor homologue in Portunus trituberculatus: Molecular cloning and microbial ligand binding
文摘
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<p id="p0010">A novel class B scavenger receptor homologue was identified from Portunus trituberculatus.p>
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<p id="p0015">PtSRB transcripts were ubiquitously expressed in all the examined tissues.p>
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<p id="p0020">PtSRB transcripts were down-regulated in hemocytes to V. alginolyticus or WSSV challenge.p>
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<p id="p0025">PtSRB was distributed in the membrane and cytoplasm when overexpressed in HEK293T cells.p>
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<p id="p0030">rPtSRB bound microbial LPS with low affinity, and LTA and PGN with high affinity in vitro.p>
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