Epigallocatechin-3-gallate attenuates microcystin-LR induced oxidative stress and inflammation in human umbilical vein endothelial cells

详细信息    查看全文

• 作者：Jun Shi^a ; Huiping Deng^a ; Huichao Pan^b ; Yinjie Xu^b ; Min Zhang^b ; ^{zm19821982@hotmail.com}
• 关键词：Microcystin-LR ; Epigallocatechin-3-gallate ; Human umbilical vein endothelial cells ; Reactive oxygen species ; Angiogenesis
• 刊名：Chemosphere
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：168
• 期：Complete
• 页码：25-31
• 全文大小：1438 K
• 卷排序：168

文摘

EGCG effect on MC-LR-induced oxidative and inflammatory responses was evaluated. EGCG inhibited MC-LR-induced HUVEC death. EGCG inhibited MC-LR-induced decrease in HUVEC viability and migration. EGCG attenuated MC-LR-mediated oxidative and inflammatory responses. EGCG decreased inflammation by suppressing MC-LR-induced NF-κB activation.