Hybridization accompanying FRET event in labeled natural nucleoside-unnatural nucleoside containing chimeric DNA duplexes

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Hybridization accompanying FRET event in labeled natural nucleoside-unnatural nucleoside containing chimeric DNA duplexes

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作者：Subhendu Sekhar Bag ; ^{ssbag75@iitg.ernet.in" class="auth_mail" title="E-mail the corresponding author} ; Suman K. Das ; Manoj Kumar Pradhan ; Subhashis Jana
关键词：Oxopyrenyl uridine (OxoPyU) ; Perylenyl uridine (PerU) ; Unnatural nucleoside ; Triazolylphenanthrene nucleobase analogues (TPhenBDo) ; Natural nucleoside-unnatural nucleoside chimera ; FRET
刊名：Journal of Photochemistry and Photobiology B: Biology
出版年：2016
出版时间：September 2016
年：2016
卷：162
期：Complete
页码：669-673
全文大小：986 K

文摘

•: Non-sacrificial stability and conformation in natural/unnatural chimeric DNA
•: Pairing selectivity and stability are higher than any of the natural duplexes.
•: FRET process is established in these two chimeric DNA duplexes.
•: The design and the hybridization accompanying FRET event is a novel concept.
•: Such FRET pairs are useful for the analysis of biomolecular interactions.

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