A Periplasmic Polymer Curves Vibrio cholerae and Promotes Pathogenesis

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• 作者：Thomas M. Bartlettp>1p> ; Benjamin P. Brattonp>1p>p> ; p>p>2p> ; Amit Duvshanip>1p> ; Amanda Miguelp>3p> ; Ying Shengp>4p> ; Nicholas R. Martinp>1p> ; Jeffrey P. Nguyenp>2p> ; Alexandre Persatp>1p>p> ; p>p>8p> ; Samantha M. Desmaraisp>3p> ; Michael S. VanNieuwenhzep>5p> ; Kerwyn Casey Huangp>3p>p> ; p>p>6p> ; Jun Zhup>4p>p> ; p>p>7p> ; Joshua W. Shaevitzp>2p> ; Zemer Gitaip>1p>p> ; p>p>9p>p> ; p>p>zgitai@princeton.edup>
• 关键词：cell shape ; bacterial cytoskeleton ; periskeleton ; pathogenesis ; peptidoglycan ; fluorescent D-amino acids ; quantitative cell biology
• 刊名：Cell
• 出版年：2017
• 出版时间：12 January 2017
• 年：2017
• 卷：168
• 期：1-2
• 页码：172-185.e15
• 全文大小：5844 K
• 卷排序：168

文摘

CrvA polymers self-assemble in the periplasm at the inner curved face of the cell CrvA drives asymmetric cell-wall insertion and is required for cell curvature CrvA-mediated curvature promotes motility in dense matrices and host pathogenesis