Sirolimus and Mycophenolate Mofetil as Calcineurin Inhibitor-Free Graft-versus-Host Disease Prophylaxis for Reduced-Intensity Conditioning Umbilical Cord Blood Transplantation

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Sirolimus and Mycophenolate Mofetil as Calcineurin Inhibitor-Free Graft-versus-Host Disease Prophylaxis for Reduced-Intensity Conditioning Umbilical Cord Blood Transplantation

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作者：Nelli Bejanyan¹ ; ^{nbejanya@umn.edu" class="auth_mail" title="E-mail the corresponding author} ; John Rogosheske² ; Todd E. DeFor³ ; Aleksandr Lazaryan¹ ; Mukta Arora¹ ; Shernan G. Holtan¹ ; Pamala A. Jacobson² ; Margaret L. MacMillan⁴ ; Michael R. Verneris⁴ ; Bruce R. Blazar⁴ ; Daniel J. Weisdorf¹ ; John E. Wagner⁴ ; Claudio G. Brunstein¹
关键词：Sirolimus ; Cyclosporine ; Reduced-intensity conditioning ; Double umbilical cord blood ; Transplantation ; Graft-versus-host disease
刊名：Biology of Blood and Marrow Transplantation
出版年：2016
出版时间：November 2016
年：2016
卷：22
期：11
页码：2025-2030
全文大小：499 K

文摘

•: Sirolimus/MMF GVHD prophylaxis is well tolerated
•: Sirolimus/MMF GVHD prophylaxis results in similar rates of GVHD as compared to CSA/MMF
•: Sirolimus/MMF GVHD prophylaxis results in similar survival as compared to CSA/MMF