Severe structural and functional visual system damage leads to profound loss of vision-related quality of life in patients with neuromyelitis optica spectrum disorders

详细信息    查看全文

• 作者：Felix Schmidt^a ; ^c ; ¹ ; Hanna Zimmermann^a ; ¹ ; Janine Mikolajczak^a ; Frederike C. Oertel^a ; Florence Pache^c ; Maria Weinhold^a ; Johann Schinzel^a ; Judith Bellmann-Strobl^a ; ^b ; Klemens Ruprecht^c ; Friedemann Paul^a ; ^b ; Alexander U. Brandt^a ; ^{alexander.brandt@charite.de}
• 关键词：Neuromyelitis optica spectrum disorder ; Vision related quality of life ; Optic neuritis ; Retinal nerve fibre layer ; Visual function ; Optical coherence tomography
• 刊名：Multiple Sclerosis and Related Disorders
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：11
• 期：Complete
• 页码：45-50
• 全文大小：422 K
• 卷排序：11

文摘

Vision-related quality of life in NMOSD is more severely impaired than in MS. This is mostly caused by more devastating ON episodes in both eyes in NMOSD. Structural damage is associated with lower vision-related quality of life in NMOSD.