Metabolomics: A potential way to know the role of vitamin D on multiple sclerosis

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• 作者：Diego Luque-Có ; rdoba^a ; ^b ; ^c ; Marí ; a D. Luque de Castro^a ; ^b ; ^c ; ^{qa1lucam@uco.es}
• 关键词：CIS ; clinically isolated syndrome ; CLIA ; chemiluminescence immunoassays ; CNS ; central nervous system ; CPB ; competitive protein binding assay ; DEQAS ; vitamin D external quality assessment scheme ; EAE ; experimental autoimmune encephalomyelitis ; EBNA1 ; EBV nuclear antigen 1 ; EBV ; Epstein-Barr virus ; EDSS ; expanded disability status scale ; ELISA ; enzyme-linked immuno-sorbent assay ; IFN-β ; interferon-β ; IgG ; immunoglobulin G ; LC ; liquid chromatography ; MOG ; myelin oligodendrocyte glycoprotein ; MRI ; m
• 刊名：Journal of Pharmaceutical and Biomedical Analysis
• 出版年：2017
• 出版时间：20 March 2017
• 年：2017
• 卷：136
• 期：Complete
• 页码：22-31
• 全文大小：1463 K
• 卷排序：136

文摘

Controversy on vitamin D status–supplementation in multiple sclerosis (MS) is discussed. The suitability of analytical methods to determine vitamin D and/or metabolites is criticized. Metabolomics studies are proposed as a solution to the present controversy in the field.